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One latest examine from Yale University found that vanillin — an extract of the vanilla bean — transforms into chemicals called acetals when aerosolized. Those chemical compounds, the researchers stated, could additionally be especially irritating to the lungs and cause injury when inhaled. Studies have shown that breathing in aerosolized propylene glycol might contribute to asthma. And a 2012 case report concerned a lady who developed a situation called exogenous lipoid pneumonia after vaping for about six months.